Personalisierte Medizin in der Krebsbehandlung

Individuelle Therapieentscheidungen durch molekulare Diagnostik und datenbasierte Analyse

Vorstellung des
Forschungsbereiches

Im Bereich Personalisierte Medizin erforscht das MOLIT Institut individualisierte Therapieansätze auf Basis molekularer Tumorprofile. Ziel ist es, Behandler:innen in der Krebsmedizin dabei zu unterstützen, gezielte Therapien einzuleiten – abgestimmt auf die genetischen Besonderheiten der einzelnen Patienten.

Durch datenbasierte Auswertungen, KI-gestützte Tools und den Zugang zu komplexen molekularen Informationen soll die klinische Entscheidungsfindung in der Onkologie optimiert werden. Der Fokus liegt dabei auf der Übertragung innovativer Forschungserkenntnisse in die Praxis.

Molekulares Tumorboard

Das molekulare Profil einer Tumorerkrankung ermöglicht Behandlern in der Krebsheilkunde, eine spezialisierte, individualisierte Therapie einzuleiten. Die Diskussion und Interpretation der komplexen genomischen Befunde erfolgt interdisziplinär im Molekularen Tumorboard (MTB) in Zusammenarbeit mit externen Kliniken und Laboren unter zusätzlicher Identifikation von geeigneten klinischen Studien für die onkologischen Patient:innen.

Forschungsteam

Prof. Dr. med. Uwe Martens

Geschäftsführer
Bereichsleitung Medizin

In Zusammenmarbeit mit der Klinischen Forschungsgruppe des Tumorzentrum Heilbronn-Franken

Publikationen

Auszug unserer
Publikationen

3757376 3ITDHJV5 1 apa 3 date desc 16 https://www.molit.eu/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22FRKUJDSM%22%2C%22library%22%3A%7B%22id%22%3A3757376%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A14357963%2C%22username%22%3A%22snuhic%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fsnuhic%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Latzer%20et%20al.%22%2C%22parsedDate%22%3A%222024-08-11%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLatzer%2C%20P.%2C%20Zelba%2C%20H.%2C%20Battke%2C%20F.%2C%20Reinhardt%2C%20A.%2C%20Shao%2C%20B.%2C%20Bartsch%2C%20O.%2C%20Rabsteyn%2C%20A.%2C%20Harter%2C%20J.%2C%20Schulze%2C%20M.%2C%20Okech%2C%20T.%2C%20Golf%2C%20A.%2C%20Kyzirakos-Feger%2C%20C.%2C%20Kayser%2C%20S.%2C%20Pieper%2C%20N.%2C%20Feldhahn%2C%20M.%2C%20W%26%23xFC%3Bnsche%2C%20J.%2C%20Seitz%2C%20C.%2C%20Hadaschik%2C%20D.%2C%20Garbe%2C%20C.%2C%20%26%23x2026%3B%20Biskup%2C%20S.%20%282024%29.%20A%20real-world%20observation%20of%20patients%20with%20glioblastoma%20treated%20with%20a%20personalized%20peptide%20vaccine.%20%26lt%3Bi%26gt%3BNature%20Communications%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%206870.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-024-51315-8%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-024-51315-8%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22A%20real-world%20observation%20of%20patients%20with%20glioblastoma%20treated%20with%20a%20personalized%20peptide%20vaccine%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pauline%22%2C%22lastName%22%3A%22Latzer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henning%22%2C%22lastName%22%3A%22Zelba%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Florian%22%2C%22lastName%22%3A%22Battke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annekathrin%22%2C%22lastName%22%3A%22Reinhardt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Borong%22%2C%22lastName%22%3A%22Shao%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%22%2C%22lastName%22%3A%22Bartsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Armin%22%2C%22lastName%22%3A%22Rabsteyn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johannes%22%2C%22lastName%22%3A%22Harter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Schulze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Okech%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Golf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christina%22%2C%22lastName%22%3A%22Kyzirakos-Feger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simone%22%2C%22lastName%22%3A%22Kayser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Natalia%22%2C%22lastName%22%3A%22Pieper%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Magdalena%22%2C%22lastName%22%3A%22Feldhahn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julian%22%2C%22lastName%22%3A%22W%5Cu00fcnsche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Seitz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22Hadaschik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claus%22%2C%22lastName%22%3A%22Garbe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Till-Karsten%22%2C%22lastName%22%3A%22Hauser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22la%20Foug%5Cu00e8re%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22Biskup%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dawn%22%2C%22lastName%22%3A%22Brooke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Parker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uwe%20M.%22%2C%22lastName%22%3A%22Martens%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gerald%22%2C%22lastName%22%3A%22Illerhaus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Deborah%20T.%22%2C%22lastName%22%3A%22Blumenthal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ryan%22%2C%22lastName%22%3A%22Merrell%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Luisa%20S%5Cu00e1nchez%22%2C%22lastName%22%3A%22Lorenzo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M%5Cu00e1t%5Cu00e9%22%2C%22lastName%22%3A%22Hidv%5Cu00e9gi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paula%22%2C%22lastName%22%3A%22de%20Robles%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sied%22%2C%22lastName%22%3A%22Kebir%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%20W.%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%20W.%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthew%22%2C%22lastName%22%3A%22Williams%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexandra%20M.%22%2C%22lastName%22%3A%22Miller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Santosh%22%2C%22lastName%22%3A%22Kesari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Castro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annick%22%2C%22lastName%22%3A%22Desjardins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%20M.%22%2C%22lastName%22%3A%22Ashley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henry%20S.%22%2C%22lastName%22%3A%22Friedman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patrick%20Y.%22%2C%22lastName%22%3A%22Wen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%20C.%22%2C%22lastName%22%3A%22Neil%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabio%20M.%22%2C%22lastName%22%3A%22Iwamoto%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bence%22%2C%22lastName%22%3A%22Sipos%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karsten%22%2C%22lastName%22%3A%22Geletneky%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lars%22%2C%22lastName%22%3A%22Zender%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Glas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%20A.%22%2C%22lastName%22%3A%22Reardon%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Saskia%22%2C%22lastName%22%3A%22Biskup%22%7D%5D%2C%22abstractNote%22%3A%22Current%20treatment%20outcome%20of%20patients%20with%20glioblastoma%20%28GBM%29%20remains%20poor.%20Following%20standard%20therapy%2C%20recurrence%20is%20universal%20with%20limited%20survival.%20Tumors%20from%20173%20GBM%20patients%20are%20analysed%20for%20somatic%20mutations%20to%20generate%20a%20personalized%20peptide%20vaccine%20targeting%20tumor-specific%20neoantigens.%20All%20patients%20were%20treated%20within%20the%20scope%20of%20an%20individual%20healing%20attempt.%20Among%20all%20vaccinated%20patients%2C%20including%2070%20treated%20prior%20to%20progression%20%28primary%29%20and%20103%20treated%20after%20progression%20%28recurrent%29%2C%20the%20median%20overall%20survival%20from%20first%20diagnosis%20is%2031.9%20months%20%2895%25%20CI%3A%2025.0-36.5%29.%20Adverse%20events%20are%20infrequent%20and%20are%20predominantly%20grade%201%20or%202.%20A%20vaccine-induced%20immune%20response%20to%20at%20least%20one%20of%20the%20vaccinated%20peptides%20is%20detected%20in%20blood%20samples%20of%2087%20of%2097%20%2890%25%29%20monitored%20patients.%20Vaccine-specific%20T-cell%20responses%20are%20durable%20in%20most%20patients.%20Significantly%20prolonged%20survival%20is%20observed%20for%20patients%20with%20multiple%20vaccine-induced%20T-cell%20responses%20%2853%20months%29%20compared%20to%20those%20with%20no%5C%2Flow%20induced%20responses%20%2827%20months%3B%20P%5Cu2009%3D%5Cu20090.03%29.%20Altogether%2C%20our%20results%20highlight%20that%20the%20application%20of%20personalized%20neoantigen-targeting%20peptide%20vaccine%20is%20feasible%20and%20represents%20a%20promising%20potential%20treatment%20option%20for%20GBM%20patients.%22%2C%22date%22%3A%222024-08-11%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-024-51315-8%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2239127809%22%2C%22PMCID%22%3A%22PMC11316744%22%2C%22ISSN%22%3A%222041-1723%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%223ITDHJV5%22%5D%2C%22dateModified%22%3A%222025-07-01T16%3A41%3A24Z%22%7D%7D%2C%7B%22key%22%3A%22XGSJJQTN%22%2C%22library%22%3A%7B%22id%22%3A3757376%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vladimirova%20et%20al.%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BVladimirova%2C%20D.%2C%20Mbonu%2C%20P.%2C%20Umapathy%2C%20M.%2C%20Kothapalli%2C%20P.%2C%20Otmacic%2C%20G.%2C%20Akkad%2C%20J.%2C%20Weyersberg%2C%20S.%2C%20Martens%2C%20U.%20M.%2C%20%26amp%3B%20Jechlinger%2C%20M.%20%282022%29.%20Etablierung%20einer%20Gewebe-Pipeline%20f%26%23xFC%3Br%20multidimensionale%20Analysen%20beim%20metastasierten%20kolorektalen%20Karzinom.%20%26lt%3Bi%26gt%3BOncology%20Research%20and%20Treatment%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B45%26lt%3B%5C%2Fi%26gt%3B%28suppl%202%29%2C%205%26%23x2013%3B346.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000526456%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000526456%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Etablierung%20einer%20Gewebe-Pipeline%20f%5Cu00fcr%20multidimensionale%20Analysen%20beim%20metastasierten%20kolorektalen%20Karzinom%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Vladimirova%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P.%22%2C%22lastName%22%3A%22Mbonu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Umapathy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P.%22%2C%22lastName%22%3A%22Kothapalli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Otmacic%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Akkad%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Weyersberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22U.M.%22%2C%22lastName%22%3A%22Martens%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Jechlinger%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%227.-10.2022%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000526456%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.karger.com%5C%2FArticle%5C%2FPdf%5C%2F526456%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%22%22%2C%22language%22%3A%22%22%2C%22collections%22%3A%5B%223ITDHJV5%22%2C%22JFIT2EJS%22%2C%22ZWEHBPD6%22%5D%2C%22dateModified%22%3A%222022-10-28T08%3A59%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22RPCGXSW6%22%2C%22library%22%3A%7B%22id%22%3A3757376%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bochum%20et%20al.%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBochum%2C%20S.%2C%20Ulmer%2C%20M.%2C%20Rohlfing%2C%20S.%2C%20Schmohl%2C%20J.%2C%20L%26%23xF6%3Bffler%2C%20H.%2C%20Knott%2C%20M.%2C%20We%26%23xDF%3Bendorf%2C%20S.%2C%20H%26%23xE4%3Bnle%2C%20C.%2C%20Greiner%2C%20J.%2C%20Denzlinger%2C%20C.%2C%20Illerhaus%2C%20G.%2C%20Ganten%2C%20T.%2C%20Sipos%2C%20B.%2C%20Biskup%2C%20S.%2C%20Vladimirova%2C%20D.%2C%20Sigle%2C%20S.%2C%20Zsebedits%2C%20D.%2C%20Fegeler%2C%20C.%2C%20%26amp%3B%20Martens%2C%20U.%20M.%20%282022%29.%20ZvPM%20-%20Implementierung%20eines%20IT-gest%26%23xFC%3Btzten%20%26%23xFC%3Bberregionalen%20Molekularen%20Tumorboards%20%28MTB%29.%20%26lt%3Bi%26gt%3BOncology%20Research%20and%20Treatment%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B45%26lt%3B%5C%2Fi%26gt%3B%28suppl%202%29%2C%205%26%23x2013%3B346.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000526456%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000526456%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22ZvPM%20-%20Implementierung%20eines%20IT-gest%5Cu00fctzten%20%5Cu00fcberregionalen%20Molekularen%20Tumorboards%20%28MTB%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Bochum%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Ulmer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Rohlfing%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Schmohl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22L%5Cu00f6ffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Knott%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22We%5Cu00dfendorf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22H%5Cu00e4nle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Greiner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Denzlinger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Illerhaus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Ganten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Sipos%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Biskup%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Vladimirova%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Sigle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22D.%22%2C%22lastName%22%3A%22Zsebedits%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Fegeler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22U.M.%22%2C%22lastName%22%3A%22Martens%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%227.-10.10.2022%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000526456%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.karger.com%5C%2FArticle%5C%2FPdf%5C%2F526456%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%22%22%2C%22language%22%3A%22en%22%2C%22collections%22%3A%5B%223ITDHJV5%22%2C%22JFIT2EJS%22%5D%2C%22dateModified%22%3A%222022-10-28T08%3A49%3A50Z%22%7D%7D%5D%7D
Latzer, P., Zelba, H., Battke, F., Reinhardt, A., Shao, B., Bartsch, O., Rabsteyn, A., Harter, J., Schulze, M., Okech, T., Golf, A., Kyzirakos-Feger, C., Kayser, S., Pieper, N., Feldhahn, M., Wünsche, J., Seitz, C., Hadaschik, D., Garbe, C., … Biskup, S. (2024). A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine. Nature Communications, 15(1), 6870. https://doi.org/10.1038/s41467-024-51315-8
Vladimirova, D., Mbonu, P., Umapathy, M., Kothapalli, P., Otmacic, G., Akkad, J., Weyersberg, S., Martens, U. M., & Jechlinger, M. (2022). Etablierung einer Gewebe-Pipeline für multidimensionale Analysen beim metastasierten kolorektalen Karzinom. Oncology Research and Treatment, 45(suppl 2), 5–346. https://doi.org/https://doi.org/10.1159/000526456
Bochum, S., Ulmer, M., Rohlfing, S., Schmohl, J., Löffler, H., Knott, M., Weßendorf, S., Hänle, C., Greiner, J., Denzlinger, C., Illerhaus, G., Ganten, T., Sipos, B., Biskup, S., Vladimirova, D., Sigle, S., Zsebedits, D., Fegeler, C., & Martens, U. M. (2022). ZvPM - Implementierung eines IT-gestützten überregionalen Molekularen Tumorboards (MTB). Oncology Research and Treatment, 45(suppl 2), 5–346. https://doi.org/https://doi.org/10.1159/000526456